Product
|
Munc-18 (Ser515) Antibody
|
Cat#
|
100-32-44A
|
Unit/Weight
|
100 μg
|
Unit Price
|
$346.00
|
Species Reactivity
|
B, Ck, D, H, Mk, M, R, X
|
Tested Application(s)
|
E, IHC, WB
|
Brief Description
|
Phosphospecific Antibody, Rabbit Polyclonal Antibody
|
Specific Description
|
Syntaxin-binding protein 2 (Munc-18) is involved in intracellular vesicle trafficking and vesicle fusion with membranes. Munc-18 contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Munc-18 regulates cytotoxic granule exocytosis in natural killer (NK) cells. The function of Munc-18 is regulated by PKC phosphorylation of Ser515.
|
Storage
|
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
|
|