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Product
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Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide
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Cat#
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87-9-65
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3-letter-code
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Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr
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Sequence
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DTHFPICIFCCGCCHRSKCGMCCKT
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Unit/Weight
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0.1mg
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Unit Price
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$295.00
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MW
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2789.4
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Formula
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C113H170N34O31S9
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Disulfide Bridge
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Cys7-Cys23, Cys10-Cys13, Cys11-Cys19 ,Cys14-Cys22
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References
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M.Zasloff, Nature, 475, 389 (2002). (Review) A. Krause, S. Neitz, H.-J. Mé‹‘ert, A. Schulz, W.-G. Forssmann, P. Schulz-Knappe, and K. Adermann, FEBS Lett., 480, 147 (2000). (Original; LEAP-1) C.H. Park, E.V. Valore, A.J. Waring, and T. Ganz, J. Biol. Chem., 276, 7806 (2001). (Original; Hepcidin) H.N. Hunter, D.B. Fulton, T. Ganz, and H.J. Vogel, J. Biol. Chem., 277, 37597 (2002). (S-S Bond) R.E. Fleming and W.S. Sly, Proc. Natl. Acad. Sci. USA, 98, 8160 (2001). (Regulation of Iron Homeostasis)
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